Saussure, de Saussure or DeSaussure may refer to:
- 13580 de Saussure, an asteroid
- Collège de Saussure, Lancy, Switzerland
- Saussure (crater), a lunar crater
- Saussure (surname)
See also
- Fortunatov–de Saussure law, a principle of linguistics
- Saussure's shrew (Sorex saussurei)
- Saussurea, a genus of flowering plants
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