Ciclafrine (INNTooltip International Nonproprietary Name; developmental code names Go 3026A, W-43026A) is a sympathomimetic and antihypotensive agent of the phenethylamine family that was never marketed.[1][2][3][4]

Chemistry

Ciclafrine is a substituted phenethylamine and belongs to the class of hemiaminal ethers.

Synthesis

Ciclafrine can be prepared by the reaction of norfenefrine with cycloheptanone.[5]

Ciclafrine synthesis

See also

References

  1. ^ Elks, J. (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 271. ISBN 978-1-4757-2085-3. Retrieved 2024-08-31.
  2. ^ Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 586–. ISBN 978-0-412-46630-4.
  3. ^ Milne, G.W.A. (2018). Drugs: Synonyms and Properties. Routledge Revivals. Taylor & Francis. p. 325. ISBN 978-1-351-78990-5. Retrieved 31 August 2024.
  4. ^ Korolkovas A (1988). Essentials of medicinal chemistry. John Wiley & Sons, Incorporated. p. 405. ISBN 978-0-471-88356-2.
  5. ^ DE 2336746, Satzinger, Gerhard & Herrmann, Manfred, "2-Hydroxyphenyl-1-oxa-4-azaspiro-alkan-Derivate [2-Hydroxyphenyl-1-oxa-4-azaspiro-alkane derivatives]", published 1975-02-13, assigned to Gödecke AG 


Allikas: https://en.wikipedia.org/wiki/Ciclafrine
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