Brian or Bryan Rose may refer to:

• Brian Rose (cricketer) (born 1950), English former cricketer
• Brian Rose (baseball) (born 1976), American former baseball player
• Brian Rose (podcaster) (born 1971), American-born podcaster based in London
• Brian Rose (racing driver) (born 1979), American former stock car racing driver
• Brian Rose (boxer) (born 1985), British boxer
• C. Brian Rose, American archaeologist
• Bryan Rose (born 1943), New Zealand former long-distance runner