Anzhou or An Prefecture was a zhou (prefecture) in imperial China, centering on modern Anlu, Hubei, China. It existed (intermittently) from 550 until 1119, when the Song dynasty renamed it De'an Prefecture.

The administrative region of An Prefecture in the Tang dynasty was in modern central Hubei. It probably includes parts of modern:

• Under the administration of Xiaogan:
  • Xiaogan
  • Anlu
  • Yingcheng
  • Yunmeng County
  • Xiaochang County
• Under the administration of Suizhou:
  • Guangshui

• Anlu Commandery
• De'an Prefecture

• Shi Weile, ed. (2005). Zhongguo Lishi Diming Da Cidian (中国历史地名大词典) [Large Dictionary of Chinese Historical Place Names] (in Chinese). China Social Sciences Press. p. 1113. ISBN 7-5004-4929-1.