4α-Methylfecosterol is a metabolic intermediate of sterols made by certain fungis, can be converted to 24-Methylenelophenol by enzyme HYD1, or undergo 4-demethylation to fecosterol.[1][2]

References

  1. ^ Kuchta, T; Bartková, K; Kubinec, R (30 November 1992). "Ergosterol depletion and 4-methyl sterols accumulation in the yeast Saccharomyces cerevisiae treated with an antifungal, 6-amino-2-n-pentylthiobenzothiazole". Biochemical and Biophysical Research Communications. 189 (1): 85–91. doi:10.1016/0006-291x(92)91529-y. PMID 1449509.
  2. ^ Kuchta, T; Léka, C; Farkas, P; Bujdáková, H; Belajová, E; Russell, NJ (July 1995). "Inhibition of sterol 4-demethylation in Candida albicans by 6-amino-2-n-pentylthiobenzothiazole, a novel mechanism of action for an antifungal agent". Antimicrobial Agents and Chemotherapy. 39 (7): 1538–41. doi:10.1128/aac.39.7.1538. PMC 162777. PMID 7492100.


Allikas: https://en.wikipedia.org/wiki/4%CE%B1-Methylfecosterol
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