2-Iodobenzoic acid, or o-iodobenzoic acid, is an isomer of iodobenzoic acid.[1] The synthesis of 2-iodobenzoic acid via the diazotization of anthranilic acid is commonly performed in university organic chemistry labs. One of its most common uses is as a precursor for the preparation of IBX and Dess–Martin periodinane, both used as mild oxidants.

Synthesis

2-Iodobenzoic acid can be synthesized by a Sandmeyer reaction: the diazotization of anthranilic acid followed by a reaction with iodide.

Diazo replacement of anthranilic acid.
Diazo replacement of anthranilic acid.

See also

References

  1. ^ "2-Iodobenzoic acid". PubChem. Retrieved 2022-11-27.
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