Tres Amigos (Spanish "Three Friends") may refer to:

• Tres Amigos, river in Juan Castro Blanco National Park

• Los Tres Amigos, comic strip by Laerte
• Los Tres Amigos, fictional company in TV series Guiding Light (1980–89)

• Tres Amigos, album by Los Huracanes del Norte 1995
• Los Tres Amigos, album by Luis Miguel 2005
• "Tres Amigos", song by Astor Piazzolla
• "Tres Amigos", song by Los Huracanes del Norte
• "Tres Amigos", tango by Aníbal Troilo, composed by Enrique Cadícamo
• "Tres Amigos", 1999 single by French-Japanese jazz duo United Future Organization
• Los Tres Amigos, a contemporary latin jazz group formed by Steve Masakowski (guitar), with James Singleton (bass) and Hector Gallardo (bongos)

• Tres Amigos, brig captured in 1816 by corsair José Joaquín Almeida

• Tre Amigos, album by Swedish hip hop band Just D
• The Three Caballeros - 1944 Disney film
• Three Amigos (disambiguation)
• Amigo (disambiguation)