High Life, The High Life, or Highlife may refer to:

• The High Life (1960 film), a German film directed by Julien Duvivier
• High Life (2009 film), a Canadian adaptation of the play by Lee MacDougall (see below)
• High Life (2018 film), a science fiction film directed by Claire Denis
• The High Life (American TV series), a 1996 American sitcom
• The High Life (British TV series), a 1994–1995 British sitcom
• The Gay Life, a 1961 musical retitled The High Life for a 2005 revival
• High Life, a 1996 play by Lee MacDougall
• High Life, a 2017 web series by Luke Eve

• Highlife, a musical genre that originated in Ghana
• High Life Music, a Canadian record label

• High Life (Brian Tarquin album) or the title song, 2001
• High Life (Frankie Miller album) or the title song, 1974
• High Life (Wayne Shorter album) or the title song, 1995
• High Life (Eno and Hyde album), by Brian Eno and Karl Hyde, 2014
• High Life!, by Exit-13, 2007
• High Life, by Takashi Sorimachi, 1998
• High Life, by Gugun Blues Shelter, 2015
• Highlife (Randy Weston album), 1963
• Highlife (Sonny Sharrock album) or the title song, 1990
• The High Life (The Puppini Sisters album), 2016
• The High Life (Reef the Lost Cauze album), 2001
• The High Life, a mixtape by Mac Miller, 2009

• "High Life" (song), by Modern Romance, 1983
• "High Life", by Daft Punk from Discovery, 2001
• "High Life", by London Grammar from If You Wait, 2013
• "High Life", by Mono from Formica Blues, 1997
• "High Life", by Nelly Furtado featuring Ace Primo from The Spirit Indestructible, 2012
• "Highlife" (song), by Cypress Hill, 2000
• "Highlife", by the Dandy Warhols from Why You So Crazy, 2019
• "The High Life" (song), by Colt Ford and Chase Rice, 2014
• "The High Life", by In Fear and Faith from Imperial, 2010
• ”Highlife”, by Logic, 2023

• High Life de Belgique, a Belgian publisher
• Highlife (cellular automaton)
• Miller High Life, an American beer
• High Life, a 2010 novel by Matthew Stokoe
• High Life, an in-flight magazine for British Airways

• Low Life (disambiguation)