"The Beginning and the End" may refer to:

• The Beginning and the End (Bizzy Bone album), 2004
• The Beginning and the End (Clifford Brown album), 1973
• The Beginning and the End (1960 film), a 1960 Egyptian film
• The Beginning and the End (1993 film), a 1993 Mexican film
• The Beginning and the End (novel), by Naguib Mahfouz
• "The Beginning and the End" (Millennium), an episode from season two of the TV fictional mystery series Millennium
• The Beginning and the End, or "Knockin' on Heaven's Door", an episode of Neon Genesis Evangelion
• "The Beginning and the End", a song by Orchestral Manoeuvres in the Dark from the album Architecture & Morality
• "The Beginning and the End", a song by Isis from the album Oceanic
• The Beginning and the End, an Islamic historical chronicle book by Ibn Kathir

• The Beginning of the End (disambiguation)
• Alpha and Omega, an appellation of God in the Book of Revelation
• First and Last (disambiguation)