Laupäev, aprill 05, 2025

Aja viide. Aja lugu.

Martin Helme

Cell signaling: lipid signaling

Extracellular

Eicosanoids	Classic: Eoxins; Leukotrienes (LTR) Prostacyclin (IPR) Prostaglandins (PGR) Thromboxane (TXR) Nonclassic: EETs Endocannabinoids (CBR) Epi-lipoxins (FPR2) Hepoxilins Isoprostanes Lipoxins (FPR2) Oxoeicosanoids (OXER) Resolvins (FPR2)
Lysophospholipids	LPA (LPAR) S1P (S1PR)
Steroids	Bile acids (GPBAR) Neurosteroids Pheromones (VNR)
Others	PAF (PAFR) Retinal (RHO)

Intracellular

Nuclear receptor	Steroids: Sex steroids: Androgens (AR) Estrogens (ER) Progestogens (PR); Corticosteroids: Glucocorticoids (GR) Mineralocorticoids (MR); Others: Bile acids (FXR) Calcitriol (VDR); Others: Eicosanoids (PPAR) Free fatty acids (PPAR) Retinoic acid (RAR, RXR)
Second messenger	General: Arachidonic acid DAG (PKC, TRPC) IP₃ (IP₃R, RyR) Phosphatidic acid Phosphoinositides: PIP₂ (IRKs) PIP₃ (PKB/Akt, Btk, PDPK1) PtdIns(3,4)P₂ (PKB/Akt, PDPK1); Sphingolipids: C1P Ceramide (CAPPs, KSR1, PKCζ, CTSD) Glucosylceramides S1P Sphingosine (SDK1, PKH, YPK)

Precursors

General	Fatty acids (ω-3, ω-6)
Steroids	Squalene Lanosterol Cholesterol

Allikas: http://en.wikipedia.org/wiki/Template:Lipid_signaling

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Tallinn

Tallinn, EE

11:37 e.l., apr. 5, 2025

0°C

scattered clouds

Humidity: 55 %

Pressure: 1016 mb

Wind: 26 Km/h

Wind Gust: 44 Km/h

Clouds: 40%

Visibility: 10 km

Sunrise: 6:34 am

Sunset: 8:12 pm