Taxoid 7beta-hydroxylase (EC 1.14.13.147) is an enzyme with systematic name taxusin,NADPH:oxygen 7-oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- taxusin + O2 + NADPH + H+ 7beta-hydroxytaxusin + NADP+ + H2O
Taxoid 7beta-hydroxylase requires cytochrome P450.
References
- ^ Chau M, Jennewein S, Walker K, Croteau R (May 2004). "Taxol biosynthesis: Molecular cloning and characterization of a cytochrome P450 taxoid 7 beta-hydroxylase". Chemistry & Biology. 11 (5): 663–72. doi:10.1016/j.chembiol.2004.02.025. PMID 15157877.
External links
- Taxoid+7beta-hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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