Stefanelli is a surname of Italian origin. The name refers to:

• Benito Stefanelli (1929–1999), Italian film actor and stuntman
• Joe Stefanelli (painter) (1921–2017), American painter
• Joe Stefanelli (b. 1960), American actor and musician
• Mattia Stefanelli (b. 1993), Sammarinese footballer
• Nicholas Stefanelli, US chef and restaurant owner
• Nicolás Stefanelli (b. 1994), Argentine footballer
• Pietro Stefanelli (1835–1919), Italian entomologist
• Simonetta Stefanelli (b. 1954), Italian actress

Also:

• Teodor V. Ștefanelli (1849–1920), Romanian historian