Sinclaire is a surname. Notable people with the name include:
- Breanna Sinclairé (born c. 1991), American transgender singer
- Bratt Sinclaire, Italian Eurobeat/Italo disco producer
- Frederick Sinclaire (1881–1954), New Zealand Unitarian minister, pacifist, social critic, university professor and essayist
- Nikki Sinclaire (born 1968), British politician
- Stephanie Sinclaire (born 1954), also known as Stephanie Crawford, is a painter and director in theatre and film
- William Sinclaire, American polo player
See also
- Elexis Sinclaire, is a fictional character in the SiN first-person shooter video game series by Ritual Entertainmen
- Sinclair
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