Salt Creek may refer to:

• Salt Creek (Amargosa River tributary), California
• Salt Creek (Orange County), California
• Salt Creek (Sacramento River tributary), California
• Salt Creek (Salton Sea), California
• Salt Creek (Pueblo County, Colorado), a stream located entirely within Pueblo County, Colorado
• Salt Creek (Des Plaines River tributary), Illinois
• Salt Creek (Little Wabash River tributary), Illinois
• Salt Creek (Sangamon River tributary), Illinois
• Salt Creek (Little Calumet River tributary), Indiana
• Salt Creek (White River tributary), Indiana
• Salt Creek (Osage River), Missouri
• Salt Creek (Platte River), Nebraska
• Salt Creek (Muskingum County, Ohio), a stream located entirely within Muskingum County, Ohio
• Salt Creek (Middle Fork Willamette River tributary), Oregon
• Salt Creek (Juab County), Utah

• Salt Creek, Colorado
• Salt Creek, Oregon
• Salt Creek, South Australia
• Salt Creek, Panama, a village on Bastimentos Island, Panama

• Salt Creek (2015), a novel by Australian author Lucy Treloar
• Salt Creek Bay, on which Edithburgh is located, in South Australia
• Salt Creek Canyon massacre, June 4, 1858 massacre in Salt Creek Canyon, Utah
• Salt Creek Oil Field, located in Natrona County, Wyoming.
• Salt Creek pupfish, another name for the Death Valley pupfish
• Salt Creek Township (disambiguation)

• Salt River (disambiguation)