Rugulosin is an anthraquinoid mycotoxin with the molecular formula C30H22O10 which is produced by Penicillium species.[1][2][3] Rugulosin is hepatotoxic and is cancerogenic.[4]

References

  1. ^ "Rugulosin". Pubchem.
  2. ^ Ueno, Yoshio; Sato, Norio; Ito, Teruo; Ueno, Ikuko; Enomoto, Makoto; Tsunoda, Hiroshi (1980). "Chronic Toxicity and Hepatocarcinogenicity of (+) Rugulosin, an Anthraquinoid Mycotoxin from Penicillium Species: Preliminary Surveys in Mice". The Journal of Toxicological Sciences. 5 (4): 295–302. doi:10.2131/jts.5.295. PMID 7218376.
  3. ^ Ueno, Y; Ueno, I; Sato, N; Iitoi, Y; Saito, M (June 1971). "Toxicological approach to (+) rugulosin, an anthraquinoid mycotoxin of Penicillium rugulosum Thom". The Japanese Journal of Experimental Medicine. 41 (3): 177–188. PMID 5314585.
  4. ^ Eisenbrand, Gerhard; Schreier, Peter (28 May 2014). RÖMPP Lexikon Lebensmittelchemie, 2. Auflage, 2006 (in German). Georg Thieme Verlag. ISBN 978-3-13-179532-8.

Further reading

  • Eckardt, Christiane (1981). Mykotoxine in Lebensmitteln (in German). Fischer. p. 23. ISBN 978-3-437-10650-7.
  • Studies in Natural Products Chemistry. Elsevier. 24 April 2015. ISBN 978-0-444-63469-6.
  • Steyn, Pieter (2 December 2012). The Biosynthesis of Mycotoxins: A study in secondary Metabolism. Elsevier. p. 375. ISBN 978-0-323-14993-8.
  • Pirttilä, Anna Maria; Frank, A. Carolin (11 July 2011). Endophytes of Forest Trees: Biology and Applications. Springer Science & Business Media. p. 244. ISBN 978-94-007-1599-8.
  • Nicolaou, K. C.; Lim, Yee Hwee; Piper, Jared L.; Papageorgiou, Charles D. (1 April 2007). "Total Syntheses of 2,2'-epi-Cytoskyrin A, Rugulosin, and the Alleged Structure of Rugulin". Journal of the American Chemical Society. 129 (13): 4001–4013. doi:10.1021/ja0685708. ISSN 0002-7863. PMID 17355133.
  • Mondal, Amit; Singh, Shailesh Kumar; Manna, Tanaya; Husain, Syed Masood (17 March 2020). "Chemoenzymatic, biomimetic total synthesis of (−)-rugulosin B, C and rugulin analogues and their biosynthetic implications". Chemical Communications. 56 (22): 3337–3340. doi:10.1039/D0CC00406E. ISSN 1364-548X. PMID 32090214. S2CID 211262650.
  • Nicolaou, K. C.; Lim, Yee Hwee; Papageorgiou, Charles D.; Piper, Jared L. (2005). "Total Synthesis of (+)-Rugulosin and (+)-2,2′-epi-Cytoskyrin A through Cascade Reactions". Angewandte Chemie International Edition. 44 (48): 7917–7921. doi:10.1002/anie.200503678. ISSN 1521-3773. PMID 16342134.
  • Sumarah, Mark W.; Miller, J. David; Adams, Gregory W. (1 September 2005). "Measurement of a rugulosin-producing endophyte in white spruce seedlings". Mycologia. 97 (4): 770–776. doi:10.1080/15572536.2006.11832768. ISSN 0027-5514. PMID 16457346. S2CID 218590435.


Allikas: http://en.wikipedia.org/wiki/Rugulosin
No tags for this post.