The diocese of Cần Thơ (Latin: Dioecesis Canthoënsis) is a Roman Catholic diocese of Vietnam.

The creation of the diocese in present form was declared November 24, 1960.

The diocese covers an area of 13,257 km² (5,119 sq mi), and is a suffragan diocese of the Archdiocese of Ho Chi Minh city.

By 2004, the diocese of Cần Thơ had about 176,424 believers (3% of the population), 153 priests and 131 parishes.^[1]

Sacred Heart Cathedral in Cần Thơ has been assigned as the Cathedral of the diocese.^[2]

Ordinaries			Coat of Arms	Period in office	Status	Reference
Vicars Apostolic of Cần Thơ
1		Bishop Paul Nguyễn Văn Bình		September 20, 1955 – November 24, 1960	Later Archbishop of Saigon	[3]
Bishops of Cần Thơ
1		Bishop Philippe Nguyễn Kim Ðiền, P.F.J.		November 24, 1960 – September 30, 1964	Later Coadjutor Archbishop of Hue	[4]
2		Bishop Jacques Nguyễn Ngọc Quang		March 22, 1965 – June 20, 1990	Died in office
3		Bishop Emmanuel Lê Phong Thuận		June 20, 1990 – October 17, 2010
4		Bishop Stephanus Tri Bửu Thiên		October 17, 2010 – present	Current Bishop

• Jacques Nguyễn Ngọc Quang (22 March 1965 - 11 March 1968)
• Emmanuel Lê Phong Thuận (6 June 1975 - 20 June 1990)
• Stephanus Tri Bửu Thiên (26 November 2002 - 17 October 2010)
• Peter Lê Tấn Lợi (25 March 2023 - 1 January 2025)

• Antoine Nguyễn Văn Thiện (incardinated here in 1955), appointed Bishop of Vĩnh Long in 1960
• Louis Hà Kim Danh (incardinated priest here, 1955-1965), appointed Coadjutor Bishop of Phú Cường in 1982 and later succeeded
• Jean-Baptiste Phạm Minh Mẫn, appointed Coadjutor Bishop of Mỹ Tho and later Archbishop of Hồ Chi Minh City (elevated to Cardinal in 2003)
• Antoine Vũ Huy Chương, appointed Bishop of Hưng Hóa in 2003 and later Bishop of Đà Lạt

10°01′38″N 105°47′05″E / 10.0271°N 105.7848°E / 10.0271; 105.7848