Ragusa may refer to:

• Ragusa, Dalmatia, the historical name of the city of Dubrovnik
• the Republic of Ragusa (or Republic of Dubrovnik), the maritime city-state of Ragusa
• Ragusa Vecchia, historical Italian name of Cavtat, a town in Dubrovnik-Neretva County, Croatia

• Ragusa, Sicily, an Italian city and commune in Sicily
• Ragusa Ibla, a historic quarter of the Sicilian city
• Province of Ragusa, Italy, one of the administrative divisions of Sicily

• Ragusa (surname)

• City of Ragusa, a sailboat
• Ragusa (chocolate), a range of products from Swiss chocolate-maker Camille Bloch, taking their name from the Croatian town.
• Ragusa (horse), a racehorse
• Ragusa Calcio, an Italian association football club located in Ragusa, Italy
• University of Ragusa, located in Ragusa and Ragusa Ibla, Italy, and founded in 1998
• Count of Ragusa, the title of Geoffrey, son of Roger I of Sicily
• Duke of Ragusa (disambiguation)

• Ragusan (disambiguation)