In enzymology, a piperidine N-piperoyltransferase (EC 2.3.1.145) is an enzyme that catalyzes the chemical reaction

(E,E)-piperoyl-CoA + piperidine CoA + N-[(E,E)-piperoyl]-piperidine

Thus, the two substrates of this enzyme are (E,E)-piperoyl-CoA and piperidine, whereas its two products are CoA and [[N-[(E,E)-piperoyl]-piperidine]].

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is (E,E)-piperoyl-CoA:piperidine N-piperoyltransferase. Other names in common use include piperidine piperoyltransferase, and piperoyl-CoA:piperidine N-piperoyltransferase.

• Geisler JG, Gross GG (1990). "The biosynthesis of piperine in Piper nigrum". Phytochemistry. 29 (2): 489–492. doi:10.1016/0031-9422(90)85102-L.