Palermo is an unincorporated community in Lincoln County, West Virginia, United States. Palermo is located on the Mud River and County Routes 46 and 58, 7.9 miles (12.7 km) south-southeast of Hamlin.[2] Palermo had a post office, which closed on February 1, 1997.[3]

The community was named after Palermo, Sicily.[4]

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