Ophelia is a character from William Shakespeare's Hamlet.

Ophelia or Ofelia may also refer to:

• Ophélia (1963 film)
• Ophelia (2018 film)
• "Ophelia", an episode of Ergo Proxy

• The Ophelias (California band), a San Francisco neo-psychedelic band of the late 1980s
• The Ophelias (Ohio band), an American rock band
• Ophelia Records, a record label by American musician Seven Lions
• Ophelia (album), an album by Natalie Merchant

• "Ophelia" (The Band song)
• "Ophelia" (The Lumineers song) (2016)
• "Ophelia", by Tori Amos from Abnormally Attracted to Sin
• "Ophelia", by L'Arc-en-Ciel from Awake
• "Ophelia", by Dawnstar
• "Ophelia", by Peter Hammill from Sitting Targets
• "Ophelia", by Kashmir from No Balance Palace
• "Ophelia", by Kaya
• "Ophelia", by French singer-songwriter Nolwenn Leroy
• "Ophelia", by Nikola Šarčević from Freedom to Roam
• "Ophelia", by Kula Shaker from Pilgrims Progress
• "Ophelia", by Tear Garden from Tired Eyes Slowly Burning
• "Ophelia", by Natalie Merchant from Ophelia
• "Ophelia", by PinkPantheress from Heaven Knows

• Ophelia (painting), an 1852 painting by John Everett Millais
• Ophelia (Cabanel), an 1883 painting by Alexandre Cabanel
• Ophelia, an 1870 painting by Pierre Auguste Cot
• Ophelia, a painting by Arthur Hughes
• Ophelia, an 1895 painting by Paul Steck
• Ophelia, any of several paintings by John William Waterhouse
• Ophelia, a circa 1900 painting by Friedrich Heyser

• Ophelia, Virginia, United States, an unincorporated community
• Ofelia Island, Graham Land, Antarctica
• Ofelia Plads, a public area in Copenhagen, Denmark
• Ophelia (moon), a moon of Uranus
• 171 Ophelia, an asteroid

• HMS Ophelia, a Royal Navy M-class destroyer launched in 1915
• German hospital ship Ophelia, a German hospital ship completed in 1912

• Ophelia (given name), people and fictional characters with the name Ophelia or Ofelia
• Flora Ofelia (born 2005), Danish singer and actress

• List of storms named Ophelia or Ofelia

• All pages with titles containing Ofelia
• All pages with titles containing Ophelia