Nicholas Charles (died 1613) was an English officer-at-arms.

Nic(h)olas or Nick Charles may also refer to:

• Nicholas Charles, actor in 1988 British film The Kitchen Toto
• Nicholas Charles (athlete), participated in 2002 Leeward Islands Junior Championships in Athletics
• Nick Charles (author) (born 1945), British author and alcoholism treatment expert
• Nick Charles (guitarist), Australian guitarist, performed at the Melbourne Guitar Show
• Nick Charles (politician) (born 1982), Maryland State Delegate
• Nick Charles (sportscaster) (1946–2011), American sportscaster

• Nick Charles, fictional character in the novel The Thin Man and adapted for film

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