Never Let Me Go may refer to:

• Never Let Me Go (1953 film), a romance starring Clark Gable and Gene Tierney
• Never Let Me Go (novel), a 2005 novel by Kazuo Ishiguro
  • Never Let Me Go (2010 film), based on the novel
• Never Let Me Go (Thai TV series), 2022

• Never Let Me Go (Placebo album), 2022
• Never Let Me Go (Mark Murphy album), 2010 by Mark Murphy
• Never Let Me Go (Luther Vandross album), 1993
• Never Let Me Go (Stanley Turrentine album), 1963

• "Can U Be", 2024 song by ¥$, originally known as "Never Let Me Go"
• "Never Let Me Go", 2018 song by Jess Glynne, from the album Always In Between
• "Never Let Me Go" (Florence and the Machine song), 2011
• "Never Let Me Go", 2011 song by The Human League, from the album Credo
• "Never Let Me Go", 2000 song by Bono and The Million Dollar Hotel Band, from The Million Dollar Hotel soundtrack
• "Never Let Me Go" (The Black Sorrows song), 1990
• "Never Let Me Go", from the 1970 album Alone by jazz musician Bill Evans
• "Never Let Me Go", 1956 song written by Evans and Livingston and sung by Nat King Cole, from the film The Scarlet Hour
• "Never Let Me Go" (Johnny Ace song), 1954

• Never Let Go (disambiguation)
• Never Let You Go (disambiguation)