Mycinamicin III 3''-O-methyltransferase (EC 2.1.1.237, MycF) is an enzyme with systematic name S-adenosyl-L-methionine:mycinamicin III 3''-O-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + mycinamicin III S-adenosyl-L-homocysteine + mycinamicin IV

The enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics.

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