Michael Powell (1905–1990) was a British film director.

Michael Powell or Mike Powell may also refer to:

• Mike Powell (rugby union) (born 1978), rugby union player for the Ospreys
• Michael Powell (lacrosse) (born 1982), U.S. professional lacrosse player
• Mike Powell (cricketer, born 1975), English cricketer
• Mike Powell (cricketer, born 1977), Welsh cricketer
• Mike Powell (long jumper) (born 1963) American athlete, the world record holder in the long jump

• Michael Powell (Louisiana politician), American politician from Louisiana
• Michael Powell (Massachusetts politician), a colonial Massachusetts politician
• Mike Powell (radio executive), early British advocate of radio automation
• Michael Powell (lobbyist) (born 1963), attorney, former chairman of the U.S. Federal Communications Commission, son of Colin Powell
• Michael Powell (bookseller), owner of an American bookstore
• Michael J. Powell, American R&B musician
• Michael J. D. Powell (1936–2015), British applied mathematician
• Michael Warren Powell, American theatre artistic director, director, actor and designer