Mesodon is a genus of land snails in the family Polygyridae.

Species within the genus Mesodon include:^[2]

• Mesodon altivagus (Pilsbry, 1900) – wandering globe
• Mesodon andrewsae Binney, 1879 – balsam globe
• Mesodon clausus (Say, 1821) – yellow globelet
• Mesodon elevatus (Say, 1821) – proud globe
• Mesodon mitchellianus (I. Lea, 1839) – sealed globelet
• Mesodon normalis (Pilsbry, 1900) – grand globe
• Mesodon sanus (Clench & Archer, 1933) – squat globelet
• Mesodon thyroidus (Say, 1816) – white-lip globe
• Mesodon trossulus Hubricht, 1966 – dandy globelet
• Mesodon zaletus (Binney, 1837) – toothed globe

• Fumonelix archeri – Archer's toothed land snail (as Mesodon archeri)
• Fumonelix jonesiana – Jones' middle-toothed land snail (as Mesodon jonesianus)
• Patera clenchi – Clench's middle-toothed land snail, Mission Creek Oregonian (as Mesodon clenchi)