María Elena Calle (born 25 July 1975) is an Ecuadorian marathon runner. She placed 99th at the 2016 Olympics.[1]

Calle took up running in 1984, but ran her first marathon only in 2011. She has a degree in occupational therapy from Virginia Commonwealth University where she competed for the VCU Rams track and field team.[4] She is married to Brad Lowery and works as a therapist in the United States.[2]

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