Manfredi is a surname.
Manfredi may also refer to:
Given name
- Manfredi Chiaramonte (died 1391), Sicilian nobleman
- Manfredi Nicoletti (1930–2017), Italian architect
- Manfredi Beninati (born 1970), Italian artist
Other uses
- Rocca dei Rettori or Castle of Manfredi, in Benevento, Italy
- 13225 Manfredi, an asteroid
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