Route 97, or Highway 97, may refer to:

– Olympic Dam Highway, South Australia

• British Columbia Highway 97
  • British Columbia Highway 97A
  • British Columbia Highway 97B
  • British Columbia Highway 97C
  • British Columbia Highway 97D
  • British Columbia Highway 97E (former)
  • British Columbia Highway 97W (former)

• EO97 road

• National Highway 97 (India), now part of National Highway 24

• Gukjido 97

• New Zealand State Highway 97

• Interstate 97
• U.S. Route 97
• Alabama State Route 97
• Arizona State Route 97
• Arkansas Highway 97
• Colorado State Highway 97
• Connecticut Route 97
• Florida State Road 97
  • County Road 97 (Escambia County, Florida)
    • County Road 97A (Escambia County, Florida)
• Georgia State Route 97
• Idaho State Highway 97
• Illinois Route 97
  • Illinois Route 97A (former)
• Iowa Highway 97 (former)
• Kentucky Route 97
• Louisiana Highway 97
• Maine State Route 97
• Maryland Route 97
  • Maryland Route 97A
• Massachusetts Route 97
• M-97 (Michigan highway)
• Minnesota State Highway 97
• Missouri Route 97
• Nebraska Highway 97
• New Hampshire Route 97
• County Route 97 (Bergen County, New Jersey)
• New Mexico State Road 97
• New York State Route 97
  • County Route 97 (Dutchess County, New York)
  • County Route 97 (Jefferson County, New York)
  • County Route 97 (Rockland County, New York)
  • County Route 97 (Saratoga County, New York)
  • County Route 97 (Steuben County, New York)
  • County Route 97 (Suffolk County, New York)
• North Carolina Highway 97
• North Dakota Highway 97
• Ohio State Route 97
• Oklahoma State Highway 97
• Pennsylvania:
  • Pennsylvania Route 97 (Adams County)
  • Pennsylvania Route 97 (Erie County)
• South Carolina Highway 97
• Tennessee State Route 97
• Texas State Highway 97
  • Texas State Highway Spur 97
  • Farm to Market Road 97
• Utah State Route 97
• Virginia State Route 97
• West Virginia Route 97
• Wisconsin Highway 97

• A97 road
• B97
• European route E97
• F-97 (Michigan county highway)
• N97
• Route 97 (MTA Maryland), a bus route in Baltimore, Maryland
• London Buses route 97