Leimgruber is a surname. Notable people with the surname include:
- Darcia Leimgruber (born 1989), Swiss ice hockey player
- Oskar Leimgruber (1886–1976), Swiss Politician
- Urs Leimgruber (born 1952), Swiss saxophonist
- Werner Leimgruber (1934–2025), Swiss footballer
- Wilhelm Leimgruber, Austrian luger
See also
- Leimgruber–Batcho indole synthesis, series of organic reactions
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