La Plata (Spanish for "the silver") can refer to:

• La Plata, capital and largest city of Buenos Aires Province
  • La Plata Partido, a district in Buenos Aires Province
  • Universidad Nacional de La Plata
  • La Plata Astronomical Observatory
• Mar del Plata, 2nd largest city in Buenos Aires Province
• United Provinces of the Río de la Plata
• Viceroyalty of the Río de la Plata

• Ciudad de la Plata de la Nueva Toledo, old name for Sucre, Bolivia

• La Plata, Huila, a municipality in Colombia

• La Plata (Seville Metro), a railway station

• La Plata, Maryland
• La Plata, Missouri
  • La Plata (Amtrak station)
• La Plata, Utah, ghost town
• La Plata County, Colorado
  • Durango-La Plata County Airport
• La Plata Mountains, Colorado
• La Plata Peak, Colorado

• Río de la Plata (also: River Plate), in South America
  • Rio de la Plata Basin, that flows towards the river
• Rio de la Plata (Puerto Rico), in Puerto Rico
• La Plata River (San Juan River), in the United States

• La Plata dolphin, found in coastal Atlantic waters of southeastern South America
• Battle of La Plata, in Cuba
• La Plata FC, football club from Argentina
• 1029 La Plata, asteroid