Kidamycin is an anthracycline antibiotic with anticancer activity.[1] It was first synthesized from a strain of streptomyces bacteria isolated from a soil sample.[2] In clinical trials, Kindamycin showed high effect against gram positive bacteria as well as multiple cancer models including Ehrlich ascites carcinoma, Sarcoma 180, NF-sarcoma, and Yoshida sarcoma.[3]

References

  1. ^ Furukawa, M.; Hayakawa, I.; Ohta, G.; Iitaka, Y. (1 January 1971). "Structure and chemistry of kidamycin". Tetrahedron. 31 (23): 2989–2995. doi:10.1016/0040-4020(75)80324-3.
  2. ^ Kanda, N. (Sep 1971). "A new antitumor antibiotic, kidamycin. I. Isolation, purification and properties of kidamycin". The Journal of Antibiotics. 24 (9): 599–606. doi:10.7164/antibiotics.24.599. PMID 5132247.
  3. ^ Kanda, Nobuo; Kono, Morihiro; Asano, Kazuo (1972). "A New Antitumor Antibiotic, Kidamycin". The Journal of Antibiotics. 25 (10): 553–556. doi:10.7164/antibiotics.25.553. ISSN 0021-8820. PMID 4648309.


Allikas: http://en.wikipedia.org/wiki/Kidamycin
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