John F. Kennedy High School or John F. Kennedy Catholic High School may refer to:

• John F. Kennedy High School (Montreal), in Montreal, Quebec

• John F. Kennedy School, Berlin, a primary and secondary school

• John F. Kennedy High School (Delano, California)
• John F. Kennedy High School (Fremont, California)
• John F. Kennedy High School (Los Angeles)
• John F. Kennedy High School (La Palma, California)
• John F. Kennedy High School (Richmond, California)
• John F. Kennedy High School (Sacramento, California)
• John F. Kennedy High School (Colorado), in Denver, Colorado
• John F. Kennedy High School (Connecticut), in Waterbury, Connecticut
• John F. Kennedy High School (Florida), racially segregated, for colored students
• John F. Kennedy High School (Guam), in Tumon, Guam
• John F. Kennedy High School (Illinois), In Chicago, Illinois
• John F. Kennedy High School (Iowa), in Cedar Rapids, Iowa
• John F. Kennedy High School (Louisiana), in New Orleans, Louisiana
• John F. Kennedy High School (Maryland), in Montgomery County, Maryland
• John F. Kennedy High School (Michigan), in Taylor, Michigan (closed in 2018)
• John F. Kennedy Memorial High School (Mississippi), in Mound Bayou, Mississippi
• John F. Kennedy Catholic High School (Missouri), in Manchester, Missouri (closed in 2017)
• John F. Kennedy High School (Minnesota), in Bloomington, Minnesota
• John F. Kennedy High School (Paterson, New Jersey)
• John F. Kennedy High School (Willingboro, New Jersey) (closed in 1989)
• John F. Kennedy Memorial High School (New Jersey), in Woodbridge Township, New Jersey
• John F. Kennedy High School (Bellmore, New York)
• Plainview – Old Bethpage John F. Kennedy High School in Plainview, New York
• John F. Kennedy High School (New York City)
• John F. Kennedy High School (Cheektowaga, New York)
• John F. Kennedy Catholic High School (Somers, New York)
• John F. Kennedy High School (Cleveland, Ohio)
• John F. Kennedy High School (Warren, Ohio)
• John F. Kennedy High School (Oregon), in Mount Angel, Oregon
• John F. Kennedy High School (Texas), in San Antonio, Texas
• John F. Kennedy Catholic High School (Washington), in Burien, Washington

• Kennedy Catholic High School (disambiguation)
• Bloomington Kennedy High School, in Bloomington, Minnesota
• Plainview-Old Bethpage John F. Kennedy High School, in Plainview, New York
• John F. Kennedy Preparatory High School (now The St. Nazianz Christian Center), in St. Nazianz, Wisconsin
• Robert F. Kennedy Community Schools Los Angeles, California
• Robert F. Kennedy Community High School Queens, New York