Issam Arabic: عصام is an Arabic name. Notable people with the name include:

• Issam (rapper) (born 1993), Moroccan rapper
• Issam Abdallah (1986–2023) was a Lebanese video journalist
• Issam Abdulhadi (1928–2013), Palestinian women’s rights activist
• Issam Abuanza, Islamic State politician from Palestine
• Issam El Adoua (born 1986), Moroccan footballer
• Issam Alim, member of al-Jihad
• Issam Alnajjar (born 2003), Jordanian musician and actor
• Issam Amira, Palestinian Islamic scholar and preacher
• Issam Ammour (born 1993), German bobsledder
• Issam Asinga (born 2004), Surinamese track and field sprinter
• Issam al-Attar (1927–2024), Syrian dissident politician and Islamic preacher
• Issam Awarke (born 1960), Lebanese wrestler
• Issam Badda (born 1983), Moroccan footballer
• Issam Bagdi (born 1955), Syrian politician
• Issam Baouz (born 1990), Algerian footballer
• Issam Barhoumi (born 1978), Tunisian kickboxer
• Issam Bassou (born 1998), Moroccan judoka
• Issam Al-Chalabi (1942–2025), Iraqi politician
• Issam Chaouali (born 1970), Tunisian journalist and sports commentator
• Issam Chebake (born 1989), Moroccan footballer
• Issam Chernoubi (born 1987), Moroccan taekwondo practitioner
• Issam John Darwich (born 1945), Syrian archbishop
• Issam Al-Edrissi (born 1984), Lebanese footballer
• Issam Erraki (born 1981), Moroccan professional footballer
• Issam Fares (born 1937), Lebanese businessman and politician
• Issam Hajali, Lebanese musician
• Issam Hallaq, Syrian military commander
• Issam Hamel (born 1997), Algerian rugby union player
• Issam Abu Jamra (born 1937), Lebanese military officer and politician
• Issam Jebali (born 1991), Tunisian footballer
• Issam Jellali (born 1981), Tunisian tennis player
• Issam Jemâa (born 1984), Tunisian footballer
• Issam Ben Khémis (born 1996), Tunisian footballer
• Issam Lahyani, Tunisian handball coach
• Issam El Maach (born 2001), Moroccan footballer
• Issam Mahfouz (1939–2006), Lebanese playwright, poet, and author
• Issam Mahrous, Syrian footballer
• Issam Ahmad Dibwan al-Makhlafi (born 1977), Yemeni member of al-Qaeda
• Issam Makhoul (born 1952), Israeli Arab politician
• Issam Merdassi (born 1981), Tunisian footballer
• Issam Naaman (born 1942), Lebanese lawyer, politician and author
• Issam Nassar, Palestinian historian
• Issam Nima (born 1979), Algerian long jumper
• Issam Rafea (born 1971), Syrian musician, music director and composer
• Issam Rajji (1944–2001), Lebanese singer
• Issam Al-Sabhi (born 1997), Omani footballer
• Issam al-Said (1938-1988), Iraqi painter, printmaker and architect
• Issam Sartawi (1935–1983), Palestinian cardiologist and politician
• Issam Shaitit (born 2000), Moroccan footballer
• Issam Fayel Al-Sinani (born 1984), Omani footballer
• Issam Haitham Taweel (born 1989), Egyptian tennis player
• Issam Tej (born 1979), Tunisian handball player
• Issam Tombakji (born 1960), Syrian judoka
• Issam Al Yamani, Palestinian refugee
• Issam Zahreddine (1961–2017), Syrian military officer
• Issam Al Zaim (1940–2007), Syrian economist and politician

• Izzy, one of the titular characters of Ben & Izzy, a Jordanian animated television series

• All pages with titles containing Issam
• Isam (name)
• Essam