Homebase is a British home improvement store and garden centre.

Home base or Homebase may also refer to:

• HomeBase, defunct US home improvement store
• Homebase (album), a 1991 album by DJ Jazzy Jeff and the Fresh Prince
• Homebase (novel), a novel by Shawn Wong
• Home Base, an alternate name for Area 51, a military base located in Nevada, U.S.
• An alternate name for home plate in baseball