Halocidin is an antimicrobial peptide isolated from the Halocynthia aurantium species of tunicate.[1][2] In mouse models, derivative peptides have shown efficacy in the treatment of fungicidal resistant Candida Albacans when used as a mouthwash additive.[3]

References

  1. ^ Jang WS, Kim KN, Lee YS, Nam MH, Lee IH (June 2002). "Halocidin: a new antimicrobial peptide from hemocytes of the solitary tunicate, Halocynthia aurantium". FEBS Letters. 521 (1–3): 81–6. Bibcode:2002FEBSL.521...81J. doi:10.1016/s0014-5793(02)02827-2. PMID 12067731. S2CID 45780988.
  2. ^ Jang WS, Lee SC, Lee YS, Shin YP, Shin KH, Sung BH, et al. (November 2007). "Antimicrobial effect of halocidin-derived peptide in a mouse model of Listeria infection". Antimicrobial Agents and Chemotherapy. 51 (11): 4148–4156. doi:10.1128/AAC.00635-07. PMC 2151467. PMID 17846130.
  3. ^ Shin SH, Lee YS, Shin YP, Kim B, Kim MH, Chang HR, et al. (May 2013). "Therapeutic efficacy of halocidin-derived peptide HG1 in a mouse model of Candida albicans oral infection". The Journal of Antimicrobial Chemotherapy. 68 (5): 1152–1160. doi:10.1093/jac/dks513. PMID 23302580.
Allikas: http://en.wikipedia.org/wiki/Halocidin
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