Grandis may refer to:
- Grandis (company), a technology company
- Grandis (surname)
- Eucalyptus grandis, a species of eucalyptus, also called flooded gum or rose gum
- Mitsubishi Grandis, a large multi-purpose vehicle
- Pizza Grandis, the most popular frozen pizza in Norway
- subspecies and hybrids
- Dactylorhiza × grandis, an orchid hybrid between D. fuchsii and D. praetermissa found in Western Europe
- Orobanche californica ssp. grandis, a subspecies of the California broomrape, a plant native to western North America from British Columbia to Idaho to Baja California
- Strix ocellata ssp. grandis, a subspecies of the mottled wood owl, a large owl species found in India
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