The enzyme glucuronan lyase (EC 4.2.2.14) catalyzes the following process:

Eliminative cleavage of (1→4)-β-D-glucuronans to give oligosaccharides with 4-deoxy-β-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is (1→4)-β-D-glucuronan lyase. This enzyme is also called (1,4)-β-D-glucuronan lyase.

• Courtois B, Courtois J (1997). "Identification of glucuronan lyase from a mutant strain of Rhizobium meliloti". Int. J. Biol. Macromol. 21 (1–2): 3–9. doi:10.1016/S0141-8130(97)00033-0. PMID 9283009.