Aja viide. Aja lugu.

Gingipain K (EC 3.4.22.47, Lys-gingipain, PrtP proteinase) is an enzyme.^[1]^[2] This enzyme catalyses the following chemical reaction:

Endopeptidase with strict specificity for lysyl bonds

Activity of this enzyme is stimulated by glycine.

References

^ Pike R, McGraw W, Potempa J, Travis J (January 1994). "Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins". The Journal of Biological Chemistry. 269 (1): 406–11. PMID 8276827.
^ Curtis MA, Aduse Opoku J, Rangarajan M, Gallagher A, Sterne JA, Reid CR, Evans HE, Samuelsson B (December 2002). "Attenuation of the virulence of Porphyromonas gingivalis by using a specific synthetic Kgp protease inhibitor". Infection and Immunity. 70 (12): 6968–75. doi:10.1128/iai.70.12.6968-6975.2002. PMC 132948. PMID 12438376.

Gingipain+K at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Proteases: cysteine proteases (EC 3.4.22)
Caspase	Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase 13 Caspase 14
Fruit-derived	Papain Ficain Bromelain Actinidain
Calpain	CAPN1 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 CAPNS1 CAPNS2
Cathepsin	B C F H K L1/L2 O S W Z
Other	Clostripain Cancer procoagulant Separase Autophagin Cruzipain 3C-like protease Gingipain R Gingipain K

Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)