Geno may refer to:

• Geno (given name), including a list of people with the name
• Marián Geňo (born 1984), Czech footballer
• Evgeni Malkin (born 1986), Russian ice hockey player nicknamed Geno

• "Geno" (song), a 1980 song by Dexys Midnight Runners
• Geno (album), a compilation album by Dexys Midnight Runners
• Geno (Super Mario RPG), a fictional character in Super Mario RPG
• Geno Studio, a Japanese animation studio
• Geno, a fictional character in Fortnite Battle Royale

• Geno Biosphere Reserve, Iran

• Genos (disambiguation)
• Gino (disambiguation)
• Gino's (disambiguation)