Fusidane or 29-norprotostane is a tetracyclic triterpene and the parent structure of a series of steroids, such as the antibiotics fusidic acid,[1][2] helvolic acid, and cephalosporin P1.[3]

Fusidic acid

See also

References

  1. ^ Zhao M, Gödecke T, Gunn J, Duan JA, Che CT (2013). "Protostane and Fusidane Triterpenes: A Mini-Review". Molecules. 18 (4): 4054–4080. doi:10.3390/molecules18044054. PMC 3901436. PMID 23563857.
  2. ^ Chen MM, Wang FQ, Lin LC, Yao K, Wei DZ (2012). "Characterization and application of fusidane antibiotic biosynethsis enzyme 3-ketosteroid-∆1-dehydrogenase in steroid transformation". Appl Microbiol Biotechnol. 96 (1): 133–142. doi:10.1007/s00253-011-3855-5. PMID 22234537. S2CID 2893266.
  3. ^ Li, Xiangchen; Cheng, Jian; Liu, Xiaonan; Guo, Xiaoxian; Liu, Yuqian; Fan, Wenjing; Lu, Lina; Ma, Yanhe; Liu, Tao; Tao, Shiheng; Jiang, Huifeng (1 October 2020). "Origin and Evolution of Fusidane-Type Antibiotics Biosynthetic Pathway through Multiple Horizontal Gene Transfers". Genome Biology and Evolution. 12 (10): 1830–1840. doi:10.1093/gbe/evaa163. PMC 7750971.
Allikas: http://en.wikipedia.org/wiki/Fusidane
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