Exoribonuclease H (EC 3.1.13.2) is an enzyme.[1] This enzyme catalyses the following chemical reaction

3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid

This is a secondary reaction to the RNA 5'-end directed cleavage 13-19 nucleotides from the RNA end performed by EC 3.1.26.13 (retroviral ribonuclease H).

References

  1. ^ Schatz O, Mous J, Le Grice SF (April 1990). "HIV-1 RT-associated ribonuclease H displays both endonuclease and 3'----5' exonuclease activity". The EMBO Journal. 9 (4): 1171–6. PMC 551793. PMID 1691093.
Allikas: http://en.wikipedia.org/wiki/Exoribonuclease_H
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