An epidemic is a disease that spreads rapidly.

Epidemic may also refer to:

• A particular epidemic; see list of epidemics
  • COVID-19 pandemic (2019–present) of COVID-19 caused by SARS-CoV-2
  • Spanish flu (1918–1920) of influenza caused by H1N1 influenzavirus
  • Black Death (14th century) of bubonic plague caused by Yersinia pestis
  • Plague of Justinian (6th century) of plague caused by Yersinia pestis

• Epidemic!, a 1961 novel by Frank G. Slaughter
• Of The Epidemics, a medical book by Hippocrates

• Epidemic (band), a San Francisco Bay Area thrash metal band from the late 1980s and early 1990s
• Epidemic Records, a record label
• Epidemic Sound, a global royalty-free soundtrack provider based in Sweden

• Epidemic (album), a 1989 album by Polish heavy metal band Turbo
• Epidemic (EP), a 2014 EP by New Years Day
• E.P.idemic, a 2004 EP by Craig's Brother
• The Epidemics, a 1986 pop album by Indian violinist L. Shankar and British musician Caroline

• "Epidemic" (song), by Polo G
• "Epidemic", a song by Slayer on the 1986 album, Reign in Blood
• "Epidemic", a song by New Years Day on the 2014 EP, Epidemic

• Epidemic (film), a 1987 film
• Epidemic (video game), a first-person shooter video game
• Epidemic Marketing, a former viral marketing company
• Epidemic, the original Russian title of To the Lake, a 2019 television series

• All pages with titles beginning with epidemic
• All pages with titles containing epidemic or epidemics
• Epidemic of Violence
• Sexidemic
• Endemic
• Pandemic (disambiguation)