ent-Pimara-9(11),15-diene synthase (EC 4.2.3.31, PMD synthase) is an enzyme with systematic name ent-copalyl-diphosphate diphosphate-lyase (ent-pimara-9(11),15-diene-forming).[1] This enzyme catalyses the following chemical reaction

ent-copalyl diphosphate ent-pimara-9(11),15-diene + diphosphate

This enzyme is involved in the biosynthesis of the diterpenoid viguiepinol and requires Mg2+, Co2+, Zn2+ or Ni2+ for activity.

References

  1. ^ Ikeda C, Hayashi Y, Itoh N, Seto H, Dairi T (January 2007). "Functional analysis of eubacterial ent-copalyl diphosphate synthase and pimara-9(11),15-diene synthase with unique primary sequences". Journal of Biochemistry. 141 (1): 37–45. doi:10.1093/jb/mvm004. PMID 17148547.


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