The English toponymic surname Egerton may refer to:

• Alfred Egerton (1854–1890), British politician
• Algernon Egerton (1825–1891), British politician
• Lady Alice Egerton (1923–1977), British courtier
• Arthur Egerton, 3rd Earl of Wilton (1833–1885), British peer and politician
• Edward Egerton (1816–1869), British politician
• Sir Edwin Egerton (1841–1916), British ambassador
• Egerton Reuben Stedman (1872–1946), Canadian politician
• George Egerton, 2nd Earl of Ellesmere (1823–1862), British peer and politician
• Sir Roland Egerton, 1st Baronet (died 1646), English landowner and politician
• Samuel Egerton (1711–1780), British politician
• Scroop Egerton, 1st Duke of Bridgewater (1681–1744), British peer and courtier
• Wilbraham Egerton (MP died 1856) (1781–1856), British landowner and politician
• Wilbraham Egerton, 1st Earl Egerton (1832–1909), British nobleman, businessman and politician
• William Egerton (originally William Tatton) (1749–1806), English politician

• Billy Egerton (1891–1934), English footballer
• Bob Egerton (born 1963), Australian rugby player
• David Egerton (1961–2021), English former rugby union player

• Caledon Egerton (1814–1874), British Army general
• Ernest Albert Egerton (1897–1966), English soldier, Victoria Cross recipient
• George Egerton (Royal Navy officer) (1852–1940), British admiral
• Lebbeus Egerton (1773–1846), Vermont militia officer, farmer, lieutenant governor

• Daniel Egerton (1772–1835), English actor
• Daniel Thomas Egerton (1797–1842), British landscape painter
• Elizabeth Egerton (1626–1663), English writer
• Frank Egerton (born 1959), British novelist
• Helen Merrill Egerton (1866–1951), Canadian writer
• Judy Egerton (1928–2012), Australian-born British art historian and curator
• Julian Egerton (1848–1945), British clarinetist
• Sarah Fyge Egerton (1670–1723), English poet
• Sarah Egerton (actress) (1782–1847), English actress
• Seymour Egerton, 4th Earl of Wilton (1839–1898), British peer and musician
• Tamsin Egerton (born 1988), English actress and model
• Taron Egerton (born 1989), Welsh actor

• Henry Egerton (died 1746), British clergyman, Bishop of Hereford
• Jack Egerton (1918–1998), Australian trade unionist
• Walter Egerton (1858–1947), British colonial administrator

• Charles Egerton (disambiguation)
• Francis Egerton (disambiguation)
• John Egerton (disambiguation)
• Philip Egerton (disambiguation)
• Stephen Egerton (disambiguation)
• Thomas Egerton (disambiguation)

• Egerton Cecil (1853–1928), English cricketer
• Sir Egerton Coghill (1853–1921), Irish painter
• Egerton Leigh (1815–1876), British soldier, landowner, politician and author
• Egerton Marcus (born 1965), Canadian retired boxer
• Egerton Herbert Norman (1909–1957; better known as E. Herbert Norman, E. H. Norman, or simply Herbert Norman), a Canadian diplomat accused of being a Communist who committed suicide
• Egerton Ryerson (1803–1882), Canadian Methodist minister, educator, politician and public education advocate
• Egerton Ryerson Young (1840–1909), Canadian teacher, Methodist missionary, lecturer, and author
• Egerton Swartwout (1870–1943), American architect
• Egerton Ryerson Young (1840–1909), author of My Dogs in the Northland (1902), which Jack London used as source material for The Call of the Wild (1903)

• Egerton family, British aristocratic family