The enzyme dimethylaniline-N-oxide aldolase (EC 4.1.2.24) catalyzes the chemical reaction

N,N-dimethylaniline N-oxide N-methylaniline + formaldehyde

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is N,N-dimethylaniline-N-oxide formaldehyde-lyase (N-methylaniline-forming). Other names in common use include microsomal oxidase II, microsomal N-oxide dealkylase, and N,N-dimethylaniline-N-oxide formaldehyde-lyase.

References

  • Machinist JM, Orme-Johnson WH, Ziegler DM (1966). "Microsomal oxidases. II. Properties of a pork liver microsomal N-oxide dealkylase". Biochemistry. 5 (9): 2939–43. doi:10.1021/bi00873a025. PMID 5961882.


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