De Wolfe, DeWolfe, or de Volfe is a surname.

• Barbara DeWolfe (1912–2008), American ornithologist
• Billy De Wolfe (1907–1974), American actor
• Chris DeWolfe (born 1966), American entrepreneur
• Elsie de Wolfe (1859–1950), American actress, interior decorator, and society figure
• Harry DeWolf (1903–2000), Canadian naval officer during the Second World War
• James P. deWolfe (1896–1966), American Episcopal priest and bishop
• Roland De Wolfe (born 1979), British professional poker player

• DeWolf (disambiguation)
• DeWolf family
• De Wolf
• Dewolfe
• De Wolfe Music - British production music company, originator of library music.
• Wolf (name)
• Wolfe (surname)
• All pages with titles containing De Wolfe
• Wulf, common Germanic name element