David Lane may refer to:

• David J. Lane (astronomer) (born 1963), Canadian astronomer at Saint Mary's University
• David A. Lane (born 1945), American professor of statistics and economics at the University of Modena and Reggio Emilia
• David C. Lane (born 1956), American professor of philosophy
• David Lane (oncologist) (born 1952), British researcher and discoverer of the p53 gene

• David Lane (director) (born 1940), British television and film director
• David Lane (musician) (born 1981), Australian musician with You Am I
• David Ian (born David Ian Lane, 1961), English stage actor and producer

• David Campbell Lane, state legislator in Florida
• David J. Lane (ambassador) (born 1960), U.S. ambassador to the United Nations Agencies for Food and Agriculture
• David Lane (British politician) (1922–1998), British Conservative Party politician
• David Lane (activist) (born c. 1955), American social conservative Christian activist
• David Lane (Massachusetts politician) (1927–2020), Massachusetts state representative

• David Lane (cricketer) (born 1965), Montserratian cricketer
• David Lane (white supremacist) (1938–2007), American white supremacist
• David Lane tram stop, a tram stop on the Nottingham Express Transit