D75-4590 is an antifungal pyridobenzimidazole derivative that inhibits β-glucan synthesis. D11-2040 and D21-6076 are antifungal derivatives of D75-4590.[1][2]

References

  1. ^ Kitamura, Akihiro; Someya, Kazuhiko; Hata, Masato; Nakajima, Ryohei; Takemura, Makoto (2008). "Discovery of a Small-Molecule Inhibitor of β-1,6-Glucan Synthesis". Antimicrobial Agents and Chemotherapy. 53 (2): 670–7. doi:10.1128/AAC.00844-08. PMC 2630612. PMID 19015325.
  2. ^ Kitamura, Akihiro; Someya, Kazuhiko; Okumura, Ryo; Hata, Masato; Takeshita, Hiroshi; Nakajima, Ryohei (2010). "In Vitro Antifungal Activities of D11-2040, a β-1,6-Glucan Inhibitor, with or without Currently Available Antifungal Drugs". Biological & Pharmaceutical Bulletin. 33 (2): 192–7. doi:10.1248/bpb.33.192. PMID 20118539.
Allikas: http://en.wikipedia.org/wiki/D75-4590
No tags for this post.