In enzymology, a cyclopentanol dehydrogenase (EC 1.1.1.163) is an enzyme that catalyzes the chemical reaction

cyclopentanol + NAD⁺ cyclopentanone + NADH + H⁺

Thus, the two substrates of this enzyme are cyclopentanol and NAD⁺, whereas its 3 products are cyclopentanone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is cyclopentanol:NAD⁺ oxidoreductase.

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