Cubero is the surname of:

• Vicente Aguilar Cubero (1808–1861), Costa Rican politician
• Edwin Cubero (1924–2000), Costa Rican footballer
• Fabián Cubero (born 1978), Argentine footballer
• Felisa Núñez Cubero (1924-2017), Spanish physicist
• Jaime Cubero (1926–1998), Brazilian intellectual, journalist, educator and activist
• Jhonny Cubero (born 1976), Costa Rican footballer
• Jonathan Cubero (born 1994), Uruguayan footballer
• Jorge Cubero (born 1992), Spanish former cyclist
• José Cubero Sánchez El Yiyo (1964–1985), Spanish bullfighter
• José Ignacio Cubero (born 1974), Basque lawyer, legal scholar and professor of law
• José María Movilla Cubero (born 1975), Spanish footballer
• José Miguel Cubero (born 1987), Costa Rican footballer
• Linda Garcia Cubero (born 1958), first Hispanic woman to graduate from any U.S. military service academy
• Pedro Cubero (1645-c. 1697), Spanish priest and world traveler
• Ruben A. Cubero (born 1939), United States Air Force brigadier general
• Sergio Cubero (born 1999), Spanish footballer
• Vicente T. Cubero, also known as Captain Francisco Salazar (1911–1942), Filipino World War II guerrilla leader